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Work with us to create the future of medicine:

We are seeking a dedicated and innovative Senior Cell Culture Scientist with good manufacturing practice (GMP) experience, to join our dynamic team. The successful candidate will play a pivotal role in generating novel cell lines for producing red blood cell-based therapeutics and will have a role in the development and maintenance of the associated quality processes. The candidate will have a strong background in mammalian cell culture, coupled with extensive experience working under pharmaceutical quality systems, particularly related to GMP. Possessing extensive knowledge of mammalian cell culture and its applications, you will help drive forward our innovative red blood cell-based technology.

Role: Senior Scientist

Application closing date: 30th November 2023

Start date: Negotiable

Salary: £45,000 – £60,000 (depending on experience)

Key responsibilities:

  • Perform, develop, optimize, and validate mammalian cell culture processes for cell line generation, culture and storage under GMP conditions.
  • Quality control: Implement rigorous quality control measures to monitor cell lines integrity, viability and contamination risks following GMP standards for record keeping and reporting
  • Documentation and record keeping: Maintain comprehensive records of all cell culture activities, including batch records, SOPs (Standard Quality operating procedures) and deviations in compliant with GMP documentation requirements.
  • Prepare all and document all cell culture media and reagents according to GMP specifications ensuring consistent and traceable production.
  • Ensure that all Equipment is properly validated and calibrated for use and maintained in accordance with GMP standards.
  • Implement and oversee sterility assurance procedures including aseptic technique and environmental monitoring to prevent contamination during cell culture processes.
  • Conduct risk assessments for cell culture processes, identifying potential issues and implementing mitigation strategies to ensure cell line product quality and safety.
  • Characterisation of donor derived erythroid cell lines using various cell biology and molecular biology techniques.
  • Help support and train other scientists in good manufacturing practice-like processes and provide experienced user input into the development and improvement of such processes.
  • Utilize various molecular biology techniques to genetically modify mammalian cell lines for specific project needs.
  • Stay updated on the latest advancements in mammalian cell line research and integrate new methodologies and technologies when applicable.
  • Regularly review and update lab SOPs (Standard Operating Procedures) to ensure alignment with appropriate quality standards.


  • Minimum of 5 years experience in mammalian cell culture and 3 years in a GMP-regulated environment.
  • Strong understanding and experience of operating under GMP, or “near GMP”.
  • Proficiency in molecular biology techniques such as PCR, qPCR, cloning, viral transduction and transfection.
  • Familiarity with analytical techniques related to cell culture, such as flow cytometry, ELISA, and Western blotting.
  • Excellent problem-solving and analytical skills.
  • Strong verbal and written communication skills.


  • Previous relevant experience in a pharmaceutical biotech or related company
  • Familiarity with high-throughput screening methods and use of automation.

Scarlet Therapeutics is proud to be an Equal Opportunity Employer, committed to fostering a diverse and inclusive work environment. We believe in the power of diverse perspectives to drive our innovation and progress. To qualify for this position, you will need to be authorized to live and work in the UK.

In your application, please send a CV and a covering letter stating your motivations and what you think you could bring to the role to

For >20 years, the team behind Scarlet have been at the forefront of blood research and its
applications in the real world. Scarlet is building a team and partners to significantly improve
patients’ lives.

Our ambition is to see our tRBCs treating patients around the world, improving their quality of
life, and continuing to push the boundaries of what science can achieve.

If you want to join our journey, we want to hear from you.